Scala Carta Foundation advances the science of medication adherence — building open frameworks, equitable access, and a global network of researchers who share a single conviction: that behavior is measurable, and measurement changes everything.
An estimated 125,000 deaths and $300 billion in avoidable healthcare costs occur annually in the United States alone — not from treatment failure, but from patients not taking their medications as prescribed.
Between 30% and 50% of patients with chronic conditions do not adhere to their prescribed regimens. Yet most interventions treat all non-adherence the same — a critical error with measurable consequences.
Scala Carta Foundation exists to change that by funding and disseminating the research infrastructure that makes precise, behavioral phenotyping of non-adherence possible at scale.
Driven by beliefs, distrust, perceived side effects, or calculated risk. Requires motivational and behavioral intervention, not reminders.
Caused by forgetfulness, complexity, access barriers, or system failures. Requires structural support and simplification.
MAP (Multidimensional Adherence Parameters) is the validated instrument that distinguishes INA from UNA, generating PEACS phenotypes that drive targeted intervention. Developed by Philip Morisky, MAP is the scientific core of TESSERA GRC.
Scala Carta Foundation is an independent 501(c)(3) pending non-profit whose mission is to advance the measurement science of medication adherence — creating open infrastructure, equitable access, and a global evidence base that clinicians can actually use.
We are not a professional society. We are not a licensing body. We are a research foundation, and TESSERA GRC is our primary vehicle for building the world's first clinician-led adherence science network, structured around the MAP instrument and PEACS phenotyping framework.
Membership is tiered to serve every stakeholder: universities running validation studies, clinics measuring patient populations, individual researchers building their evidence base, graduate students earning their first publication credit, and industry partners seeking real-world adherence data.
The global burden of medication non-adherence falls disproportionately on low- and middle-income countries, where chronic disease rates are rising fastest and research infrastructure is thinnest. TESSERA GRC was designed with this asymmetry in mind.
Through our LMIC Grant Pathway and Research Contribution License (RCL), researchers at qualifying institutions can access full TESSERA membership, including MAP instrument access and co-authorship on normative studies, at no cost.
Donor support is what makes this possible. Every contribution to Scala Carta Foundation directly funds the participation of a researcher who would otherwise be excluded from the global evidence network.
Full TESSERA membership fee waiver for researchers at institutions in World Bank-classified low- and middle-income countries.
Researchers anywhere may contribute normative MAP data in exchange for full consortium membership, including institutional access to MAP scoring and co-authorship eligibility.
Every tier contributes to the global MAP normative dataset. The tier you choose reflects the scope of your access, the depth of your data rights, and your role in shaping adherence science.
TESSERA membership includes your ATLAS workspace. The difference is what surrounds it: a TESSERA credential carries institutional weight, appears on your publications, and connects you to a network of researchers across 60+ countries. A standalone key is just access.
Post active studies, call for international co-investigators, and discover matching cohorts across 40+ countries. Research Affiliate tier and above can post; all tiers can browse and respond to open calls.
View in ATLAS ↗Scala Carta Foundation is a 501(c)(3) pending non-profit. Your donation supports LMIC researcher access, MAP validation studies, and the open evidence infrastructure that makes precision adherence science possible.
Funds one month of MAP instrument access for an LMIC researcher who cannot afford the membership fee.
Donate $100Sponsors a full Student tier membership for a graduate researcher in an LMIC country for one year.
Donate $500Funds a validation study partnership covering MAP instrument deployment, data collection support, and co-authorship in a normative dataset publication.
Donate $2,500Endows a named LMIC fellowship for one year, covering full Validation Partner membership for a researcher in a qualifying country.
Donate $10,000For wire transfer, institutional giving, or custom amounts, contact [email protected]
Scala Carta Foundation · 501(c)(3) pending · EIN issued · All donations are pending tax-deductibility
From inquiry to active membership in under two weeks for most tiers. No complex procurement process. No lengthy onboarding forms.
Fill out the membership application below with your institution, country, research focus, and preferred tier. Applications are reviewed within 1–2 business days for LMIC Research Grant applicants, and 3–5 business days for all others.
After a brief alignment call, Scala Carta Foundation issues your ATLAS workspace key provisioned for your tier and data residency region. No installation required.
Your TESSERA Study ID is issued, your team completes MAP certification, and your first assessments begin contributing to the global normative dataset.
Whether you are a single researcher, a teaching hospital, a medical or health sciences school, or a global pharmaceutical company, TESSERA GRC has a tier built for your scope of work. Every member adds one more tile to the first true map of global medication adherence.
Applications are reviewed within 5 business days. You will receive an ATLAS workspace access code and a formal membership confirmation from the Scala Carta Foundation.
Thank you for applying to TESSERA GRC. Your application has been submitted to the Scala Carta Foundation for review. A confirmation email will arrive within 24 hours, and a membership decision within 1–2 business days for LMIC applicants, or up to 5 business days for all others.